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Monday, February 14, 2011

PhD position in Fermentable sugar production process (NETHERLANDS)

Description

For this position we are looking for a candidate with the following qualifications: An MSc degree in Chemistry, Food Technology, Biotechnology or Molecular Life Sciences. Experience with analytical and/or preparative chromatography and mass spectrometry. Experience with carbohydrates and enzymology will add to the suitability of a candidate for this post. Excellent research skills. Proven interest to work on the interface of chemistry and biochemistry. Ability to work in a multi-disciplinary project. Excellent communication skills and proficiency in English (both oral and written).

Research Fields

Agricultural sciences

Benefits

We offer you a temporary position for a period of 1.5 years with extension of 2.5 years after successful evaluation. Gross salary per month € 2042 in the first year rising up to € 2612 per month in the fourth year. We not only offer a competitive salary but also good (study) leave and a pension of the ABP Pension Fund.Additional informationFor more information about this position, please contact Dr. H.A. Schols, associate professor Food Chemistry, telephone number +31 317 482239. For more information about the contractual aspects, please contact Mr. Rob van Meegen, telephone number +31 317 85466.Interested?You can apply online at www.werkenbij.wur.nl/UK until March 6th 20011
Within the framework of BE-Basic Program (www.b-basic.nl) we are looking for a PhD candidate for the project “Fermentable sugar production process”. The project is aiming at a complete (enzymatic) degradation of the polysaccharide part of crops and byproduct streams from the agro-industry. The research is part of a joint project with different research groups of Wageningen University and Research Center. Hydrolysates of completely degraded plant material containing mainly monosaccharides can be used as carbon source in various industrial fermentation processes. The main problem to be tackled for complete saccharification is the existence of insoluble and inaccessible cell wall structures, as well as soluble enzyme-resistant oligo- and polysaccharide fragments. The PhD candidate will characterize selected feed stock, evaluate pretreatment conditions to increase the accessibility of the cell walls material and to understand the effects of treatment on the interaction of lignin and polysaccharides within the cell wall architecture. The formation of limiting structures hindering further enzymatic degradation will be monitored. Subsequently, the structure of enzyme-resistant cell wall fragments will be elucidated. Novel enzymes made available by project partners will be investigated for their ability to degrade these resistant structures. Selected enzymes will be studied for their specific biochemical properties. The PhD will make use of advanced (bio)chemical methods to isolate and characterize polysaccharides and enzymes. Resistant oligo-and polysaccharides will be analyzed and characterized using various forms of analytical and preparative chromatography and Maldi Tof Tof MS, LC- and CE-MS and NMR-techniques. The PhD candidate will closely cooperate with industrial and research partners participating in the project.

Requirements

Required Education Level
DegreeUniversity Graduate
Degree FieldAgricultural sciences
Required Research Experiences
Main Research FieldAgricultural sciences
Years of Research Experience1
Required Languages
LanguageENGLISH
Language LevelGood
Company/Institute
Wageningen UR (University & Research centre)
Other
Postbus 9101
6700 HB - Wageningen
NETHERLANDS
emailmarijke.bouma@wur.nlhttp://www.wur.nl/
Application details
Application Deadline
06/03/2011

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